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Adcytherix is building an antibody-drug conjugate (ADC) powerhouse by innovating on payload and ADC design.

A major step forward in the fight against cancer and a specific response to emerging payload resistance.

ADC antibody drug conjugates
targeted cancer therapies with ADCs
targeted cancer therapies with ADCs

About us

A biopharmaceutical company

We are committed to advancing the next generation of Antibody-Drug Conjugates (ADC), driving the transition to the new era of multifunctional therapies and precision oncology. Founded by leaders with a global mindset across oncology, chemistry and drug development, Adcytherix combines deep industrial experience with an agile, execution-driven operating model.


We focus on areas of high unmet medical need, turning the latest advances in payload science, conjugation design and translational research into meaningful clinical changes. Driven by a bold ambition, our team is building a highly differentiated ADC franchise to tackle cancers that still resist today’s science and technology.

Driving the development of transformational ADC technology

At Adcytherix, we believe that innovation in payload chemistry and sophisticated conjugation engineering shape the future of ADCs. Overcoming resistance, enhancing efficacy, and fine-tuning the balance between stability and payload release are the three levers that will enable ADCs to expand the curative potential of targeted therapies.


By harnessing clinically validated payloads and integrating them into optimized, next-generation ADC designs, we aim to broaden the therapeutic window and addressable indications of ADCs in oncology. 

Transforming Innovation into Patient Impact

At Adcytherix, transforming innovation into patient impact means looking beyond the science to understand the real-world needs of people living with cancer and those who support them. A diagnosis affects not only patients, but also their families, care partners, and the broader community.

 

By designing ADCs that address resistance and deliver greater precision, tolerability, and meaningful clinical benefits, we aim to improve outcomes and quality of life. We value the insights of patients, advocacy groups, and care networks, whose experiences help shape therapies that truly meet patient needs. Our commitment extends beyond developing next-generation ADCs: we strive to be a responsible, engaged, and compassionate partner to the cancer community.

Team

Adcytherix was founded by Jack Elands and Pontifax Venture Capital.

Adcytherix is led by a seasoned management team and is supported by a network of world-leading experts in the field of ADC development. 

Management team

Jack Elands
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Jack Elands

Founder, Chief Executive Officer

Dr. Jack Elands brings extensive ADC and biotech leadership experience as founder and former CEO of Emergence Therapeutics, Talix Therapeutics, and has also served as CEO of BliNK Biomedical, co-founder and CEO of Amakem, CEO of Vitec, and co-founder of MImAbs

Jan H.M. Schellens
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Jan H.M. Schellens

Chief Medical Officer

Dr Jan Schellens is a medical oncologist and clinical pharmacologist with leadership roles as CMO at multiple biotechs, and former staff member Dept. Medical Oncology, Head Dept. Clinical Pharmacology at the Netherlands Cancer Institute and Professor at Utrecht University. With 20+ years in clinical development and 15 years in drug regulation, including Chair of the EMA Scientific Advisory Group on Oncology, he brings deep clinical and regulatory expertise

Xavier Preville
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Xavier Preville

Co-founder, VP and head of research & preclinical development

Dr. Xavier Preville is co-founder and former CSO of Emergence Therapeutics, and previously served as CSO at Talix Therapeutics and director of preclinical development at Transgene and BT Pharma (Genticel). He brings deep ADC biology and translational expertise to drive Adcytherix’s preclinical pipeline

Thierry Menguy
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Thierry Menguy

VP and head of CMC operations

Dr. Thierry Menguy, former head of CMC at LinKinVax and Chief Technical Officer and co-founder of ElsaLys Biotech. He has also held senior CMC and of large molecules R&D roles at Transgene. He brings extensive CMC leadership to secure robust, scalable development of Adcytherix’s programs

Jaime Arango
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Jaime Arango

Chief Financial Officer

Jaime Arango, MBA, brings over 20 years in biopharma experience, having served as CFO of TreeFrog Therapeutics and Medincell where he led its IPO, and previously held finance leadership roles at Biogen and Merck & Co. He brings strong strategic and financial leadership to support Adcytherix’s growth and execution

Inka Pawlitzky
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Inka Pawlitzky

VP and head of clinical development

Former senior medical director and oncology program lead at Faron Pharmaceuticals, with prior roles in oncology development at Allucent and as consultant at SMS Oncology, Dr. Inka Pawlitzky brings strong clinical strategy and trial execution expertise to advance Adcytherix’s ADC candidates

Julia Gavrilyuk
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Julia Gavrilyuk

VP and head of ADC technology development

Dr. Julia Gavrilyuk, co-founder and former CEO of Yarrow Therapeutics and senior scientist at Abbvie and Stemcentrx, brings payload and chemistry engineering expertise to shape Adcytherix’s next-generation ADC designs

Holger Karsunky
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Holger Karsunky

VP and Head of ADC Discovery

Dr. Holger Karsunky, co-founder and former CSO of Yarrow Therapeutics, and former oncology discovery leader at Abbvie Stemcentrx and Cellerant Therapeutics, brings broad discovery and preclinical experience to advance Adcytherix’s early ADC portfolio

Supervisory Committee

Jack Elands
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Jack Elands

President of Adcytherix

Iyona Rajkomar
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Iyona Rajkomar

Managing Partner at DawnBiopharma (a platform controlled by KKR)

Ohad Hammer
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Ohad Hammer

Partner at Pontifax Venture Capital

Olivier Martinez
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Olivier Martinez

Senior Investment Director at Bpifrance’s InnoBio funds

Peter Neubeck
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Peter Neubeck

Partner at Kurma Partners

Regina Hodits
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Regina Hodits

Managing Director at Angelini Ventures

Sofia Ioannidou
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Sofia Ioannidou

Partner at Andera Partners

Ximing Ding
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Ximing Ding

Principal at Pureos Bioventures

Laurent Higueret of Bpifrance, Reut Shema of aMoon, Matthew Hammond of RA Capital Management and Ran Nussbaum of Pontifax are observers on the company’s supervisory committee.

Investors

Pipeline

The Adcytherix portfolio spans multiple proprietary payload classes and targets. Our strategy is to establish a first-in-class ADC franchise capable of treating tumors that remain out of reach for current therapies. Our leading drug candidate, ADCX-020, is advancing toward clinical evaluation, supported by a €105 million Series A financing.

Building a highly differentiated ADC portfolio

ADCX-020

Leading drug candidate

€105 million Series A financing

Under clinical evaluation

Partnering for Impact

We are open to partnerships with top-level biotechs, pharmas and academics who share our ambition to accelerate next-generation ADCs. Our interests span novel payload chemistry, target discovery, and clinical translation.

News

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